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Leukodystrophy
Leukodystrophies are a group of more than 50 rare genetic diseases that affect the brain, spinal cord, and often the peripheral nerves. Each type of leukodystrophy is caused by a specific gene abnormality that leads to abnormal development or destruction of the white matter (myelin sheath) of the brain. Most leukodystrophies are inherited, although some arise spontaneously. Canavan disease is a leukodystrophy and CPN features several Canavan families.
Leukodystrophies are progressive, meaning that the effects tend to worsen throughout the life of the patient.
For more information, visit the United Leukodystrophy Foundation